Santa Cruz is the second largest island in the archipelago. An airport on the nearby island of Baltra is often a starting or ending point for Galapagos cruises, so Santa Cruz is likely to feature in your itinerary at some point. In terms of excursions, the central island has a lot to offer visitors. From sandy bays to volcanic features to lush highlands with roaming tortoises. The much hyped Charles Darwin Centre in Puerto Ayora is also included in some itineraries.